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TSAI LABORATORY AT MIT

Network level approaches to studying Neurological Disorders

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  • Li-Huei Tsai
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  • May 9, 2019
    In Neuron: Why visual stimulation may work against Alzheimer’s

    In Neuron: Why visual stimulation may work against Alzheimer’s

    Several years ago, MIT neuroscientists showed that they could dramatically reduce the amyloid plaques seen in mice with Alzheimer’s disease simply by exposing the animals to light flickering at a specific frequency. In a new study, the researchers have found that this treatment has widespread effects at the cellular level, and it helps not just…

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  • May 2, 2019
    In Nature: A comprehensive map of how Alzheimer’s affects the brain

    In Nature: A comprehensive map of how Alzheimer’s affects the brain

    MIT researchers have performed the first comprehensive analysis of the genes that are expressed in individual brain cells of patients with Alzheimer’s disease. The results allowed the team to identify distinctive cellular pathways that are affected in neurons and other types of brain cells. This analysis could offer many potential new drug targets for Alzheimer’s,…

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  • March 14, 2019
    In Cell: Brain wave stimulation may improve Alzheimer’s symptoms

    In Cell: Brain wave stimulation may improve Alzheimer’s symptoms

    By exposing mice to a unique combination of light and sound, MIT neuroscientists have shown that they can improve cognitive and memory impairments similar to those seen in Alzheimer’s patients. This noninvasive treatment, which works by inducing brain waves known as gamma oscillations, also greatly reduced the number of amyloid plaques found in the brains…

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  • January 24, 2019
    Tsai earns Hans Wigzell Research Foundation Science Prize

    Tsai earns Hans Wigzell Research Foundation Science Prize

    The Hans Wigzell Research Foundation announced Jan. 23 that neuroscientist Li-Huei Tsai, Picower Professor and director of The Picower Institute for Learning and Memory at MIT, is the winner of Hans Wigzell´s Prize in Medicine for 2018. Tsai will travel to Stockholm to receive the prize and deliver a lecture on her research Feb. 14. “The…

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  • November 8, 2018
    With fellowship, postdoc will work to solve Alzheimer’s myelin mystery

    With fellowship, postdoc will work to solve Alzheimer’s myelin mystery

    Growing up, Joel Blanchard watched his grandfather remain cognitively sharp past the age of 90 but his grandmother develop Alzheimer’s in her 70s. The difference sparked an interest in brain aging that motivates him today as a postdoc in MIT’s Picower Institute for Learning and Memory. As the new recipient of a 2018 Glenn Foundation…

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  • September 12, 2018
    With sense of humility, responsibility new MIT postdoc begins HHMI fellowship

    With sense of humility, responsibility new MIT postdoc begins HHMI fellowship

    Years before he learned that he’d be awarded a highly competitive Hanna H. Gray fellowship from the Howard Hughes Medical Institute, Matheus Victor said he was already feeling fortunate – maybe even a little guilty – simply because he had the rare opportunity to do what he loved. As a graduate student at Washington University…

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  • July 10, 2018
    Neuroscientists discover roles of gene linked to Alzheimer’s

    Neuroscientists discover roles of gene linked to Alzheimer’s

    People with a gene variant called APOE4 have a higher risk of developing late-onset Alzheimer’s disease: APOE4 is three times more common among Alzheimer’s patients than it is among the general population. However, little is known about why this version of the APOE gene, which is normally involved in metabolism and transport of fatty molecules…

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  • May 29, 2018
    Prime Minister Trudeau visits the MIT Innovation Exhibition in Boston. May 18, 2018

    Prime Minister Trudeau visits the MIT Innovation Exhibition in Boston. May 18, 2018

    Prime Minister Trudeau visits the MIT Innovation Exhibition in Boston. May 18, 2018.///Le premier ministre Trudeau visite l’Exposition sur l’innovation au MIT, à Boston. 18 mai 2018. Credit: Adam Scotti

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  • February 28, 2018
    Nature Podcast 2.28.2018

    Nature Podcast 2.28.2018

    Brainwaves and Fingerprints from the Early Universe

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  • February 28, 2018
    How flashing lights and pink noise might banish Alzheimer’s, improve memory and more

    How flashing lights and pink noise might banish Alzheimer’s, improve memory and more

    Nature News feature 2.28.2018

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