Li-Huei Tsai, Ph.D.

Li-Huei Tsai leans on a railing and smiles. A large window is in the background

Director, The Picower Institute for Learning and Memory AT MIT
Picower Professor of Neuroscience, Department of Brain and Cognitive Sciences
Senior Associate Member, Broad Institute

Massachusetts Institute of Technology
43 Vassar St. 46-4325A
Cambridge, MA 02139
Phone: 617-324-1660

Short Biography

  • Li-Huei Tsai received her Ph.D degree from the University of Texas Southwestern Medical Center at Dallas.
  • Dr. Tsai completed her postdoctoral work with Ed Harlow’s laboratory at Cold Spring Harbor laboratory and Massachusetts General Hospital.
  • In 1994, Dr. Tsai joined the faculty in the Department of Pathology at Harvard Medical School and was named an investigator of Howard Hughes Medical Institute in 1997.
  • In 2006, she was appointed Professor in the Department of Brain and Cognitive Sciences, and joined the Picower Institute for Learning and Memory at MIT.
  • In 2015, she co-founded the Aging Brain Initiative at MIT.
  • In 2019, she became co-director of the Alana Down Syndrome Center at MIT.


  • Outstanding Contributor Award, Alzheimer Research Forum
  • Alzheimer’s Research Consortium
  • Academician, Academia Sinica
  • Simons Foundation Autism Research Initiative Award
  • Member of the National Academy of Medicine
  • NIH Cantoni Lecture Award
  • Glenn Award For Research in Biological Mechanisms of Aging
  • Fellow, American Association for the Advancement of Science (AAAS)
  • Distinguished Academy Achievement Award, Chinese American Academic and Professional Society
  • The Javits Neuroscience Investigator Award
  • The Mika Salpeter Lifetime Achievement Award
  • Hans Wigzell Research Foundation Science Prize
  • Fellow, National Academy of Inventors
  • Member, American Academy of Arts and Sciences


Check out the Publications page to learn more about Dr. Li-Huei Tsai’s published research.

Photo credit: David Sella