Circuits & Systems
Cognitive deficits that occur in neurodegeneration may arise from disruptions in neural circuits and network connectivity.
Single-cell genomic analysis and machine learning
We study the transcriptomic and epigenomic landscape in the major brain cell types in both normal brain physiology and disease states.
iPSC models
Induced pluripotent stem cell (iPSC) methods are powerful for studying disease in relevant cell types derived from human sources.
In the news
In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity
Study provides new evidence that sensory stimulation of gamma-frequency brain …
Review: Evidence expanding that 40Hz gamma stimulation promotes brain health
A decade of studies from labs around the world provide …
Study reveals ways in which 40Hz sensory stimulation may preserve brain’s ‘white matter’
MIT scientists report that gamma frequency light and sound stimulation …
Study across multiple brain regions discerns Alzheimer’s vulnerability and resilience factors
Genomics and lab studies reveal numerous findings, including a key …
Congratulations Mingus Rae Zoller
Graduate student Mingus Rae Zoller has been named to the …
A noninvasive treatment for “chemo brain”
Stimulating gamma brain waves may protect cancer patients from memory …
How sensory gamma rhythm stimulation clears amyloid in Alzheimer’s mice
Stimulating a key brain rhythm with light and sound increases …
Evidence early, but emerging, that gamma rhythm stimulation can treat neurological disorders
A new review surveys a broadening landscape of studies showing …