Our lab is dedicated to conducting cutting edge scientific research that advances insight into the pathophysiology of age-related dementias such as Alzheimer’s. We are working diligently toward producing new therapeutic strategies for the millions of patients and families who motivate us.
Over the course of three-plus decades, our lab has published more than 230 original research papers, and we take great care to ensure that our work is accurate when we share it with the public. In recent months, we’ve become aware of unintentional errors in a handful of our prior publications; these errors had been previously difficult for us to spot, but were detected through the use of AI tools. When we learned of these concerns, we investigated and, when necessary, worked with the relevant journal to correct the research record through their standard editorial framework.
We remain fully confident in the validity of our results and the fundamental conclusions of our studies.
Our commitment to research integrity includes the following practices:
- We ask multiple lab members to reproduce significant discoveries to ensure that new findings are valid.
- We train all lab members in research transparency and reproducibility.
- We document our work with electronic lab notebooks.
- We have a dedicated lab data manager who ensures that all original data are properly stored.
We are very proud that our major findings and scientific discoveries have been replicated by labs around the world and have helped to provide insight into the causes of, and possible treatments for, Alzheimer’s and other dementias.
We pride ourselves on working earnestly and carefully, but we are human. While we are of course capable of error, we are also capable of learning and improving. That remains our steadfast commitment, alongside our deep dedication to understanding and fighting neurodegeneration.
Sincerely,
Li-Huei Tsai